Dual preferred retinal loci enhance visual function in patient with age-related macular degeneration
A case study presented at SECO 2025 highlights the benefits of utilizing 2 preferred retinal loci (PRLs) for fixation in low vision rehabilitation (LVR) for a patient with age-related macular degeneration. Traditionally, LVR focuses on identifying and training a single optimal PRL to maximize visual performance. However, this case demonstrated that 2 PRLs, each serving different visual functions, allowed the patient to achieve all visual goals effectively.
By understanding how age-related macular degeneration impacted retinal integrity and residual vision, clinicians tailored LVR strategies to the patient’s specific needs. Microperimetry played a crucial role in identifying and training these PRLs, ultimately leading to improved functional vision.
Clinical Insights
- PRL training is essential in LVR to enhance visual function and help patients achieve their goals.
- The choice of PRL should align with the visual task and influence device recommendations.
- In select cases, utilizing 2 PRLs for different tasks may be more beneficial than relying on a single PRL.
- Proper training in multiple PRLs can significantly improve a patient’s ability to perform daily activities.
This case underscores the importance of individualized LVR strategies and the potential advantages of training multiple PRLs for patients with central vision loss.
Reference
Knizak M, et al. Which is better: 1 or 2? Utilizing two PRLs for low vision rehabilitation. Poster presented at: SECO 2025; February 26–March 2, 2025; Atlanta, GA.

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