Key Takeaways
- Glaucoma was associated with fewer restless sleep minutes after adjustment for demographic and health factors.
- Unadjusted differences in activity and sleep measures did not persist after adjustment.
Adults with glaucoma had modest differences in physical activity and sleep compared with those without glaucoma in a large study using data from commercial wrist-worn devices.
The retrospective cross-sectional study included 40,743 adults aged 40 years or older with Fitbit data in the All of Us Research Program. Of these participants, 1,245 (3.1%) had glaucoma and contributed an average of 2.5 years of wearable data.
Before adjustment, participants with glaucoma recorded fewer daily steps, lower active calorie expenditure, and fewer lightly and fairly active minutes than controls. They also spent less time in bed and asleep, with more light sleep and less deep, REM, and restless sleep.
After adjustment for demographics, body mass index, sleep disorders, and cardiovascular disease, glaucoma remained associated with fewer restless minutes during sleep, while associations with physical activity and other measures of sleep architecture were no longer observed.
Reference
Bernstein I, Jafry S, Singh K, et al. Assessing physical activity and sleep patterns in glaucoma using wearable devices. Br J Ophthalmol. 2026;bjo-2026-329606. doi: 10.1136/bjo-2026-329606. Epub ahead of print. PMID: 42613167.
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