DOT spectacle lenses shown to effectively reduce myopia progression in children over four years

The Diffusion Optics Technology (DOT) spectacle lenses effectively slow myopia progression in children over a 4-year period, according to a study.

The study evaluated the effectiveness of Diffusion Optics Technology (DOT) spectacle lenses in controlling myopia progression in children. The CYPRESS trial (Part 1 and 2) involved 256 children aged 6-10, comparing 2 DOT lens designs (Test 1, Test 2) against standard single-vision lenses. After 3 years, 200 participants continued into the fourth year.

Test 1 lenses were found to be significantly more effective than the control lenses in reducing myopia, with a notable difference in axial length and cycloplegic spherical equivalent refraction across the 4 years. The study also noted that the COVID-19 pandemic likely impacted the treatment’s effectiveness in the second and third years due to public health restrictions.

Overall, DOT lenses were deemed safe and effective.

Reference
Laughton D, Hill JS, McParland M, et al. Control of myopia using diffusion optics spectacle lenses: 4-year results of a multicentre randomised controlled, efficacy and safety study (CYPRESS). BMJ Open Ophthalmol. 2024;9(1):e001790. doi: 10.1136/bmjophth-2024-001790. PMID: 39384223.