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Three-layer decellularized basement membrane shows greater long-term corneal staining reduction in dry eye disease

In a small retrospective series, both single- and three-layer dehydrated, decellularized basement membrane (DBM) allografts improved corneal staining in dry eye disease over 6 months, but the three-layer construct produced a significantly greater and more sustained reduction in corneal staining compared with the single-layer option. The study included 17 eyes...

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