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High-dose atropine plus dual-focus lenses show minimal myopia progression

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Key Takeaways

  1. Both high-dose atropine combinations were associated with minimal axial elongation.
  2. No significant difference in axial elongation was found between dual-focus contact lenses and multifocal spectacles.

Children treated with high-dose atropine combined with dual-focus soft contact lenses (DFCLs) showed minimal axial elongation, with no significant difference compared with high-dose atropine plus photochromatic multifocal spectacles (PMS), according to real-world data presented at the 26th Euretina Congress.

The analysis included 50 children from a myopia registry, with 31 receiving high-dose atropine (>0.5%) with DFCLs and 19 receiving atropine with PMS. During the first 6 months, mean axial elongation was 0.083 mm with atropine-DFCL and 0.063 mm with atropine-PMS (P > 0.05). From 6 to 12 months, elongation was 0.133 mm and 0.116 mm, respectively (P > 0.05).

A linear mixed-effects model also found no significant difference in treatment effect between groups. The researchers noted that both approaches were associated with minimal axial elongation and that the potential benefit of adding DFCLs for children with poor responses to atropine alone warrants further investigation.

Reference

Zebari H, et al. Real-world effectiveness of high-dose atropine combined with dual-focus soft contact lenses for myopia control in children. Presented at: 26th Euretina Congress; October 1-4, 2026; Vienna, Austria.

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