Pilocarpine eye drop 1.25% analogue (IR- Pilo) and Vuity eye drops are safe and effective for improving near vision in presbyopic patients, with IR-Pilo showing slightly greater benefits in accommodation and pupil constriction, according to a study.
The non-randomized comparative study included 75 participants aged 40 to 60, with one eye receiving either IR-Pilo (n = 45) or Vuity (n = 30) with the other eye served a control.
Results showed that both treatments significantly improved near vision (P < 0.001), with IR-Pilo demonstrating a stronger effect (4 vs 2.3). Both eye drops increased pupil constriction and amplitude of accommodation, though IR-Pilo had a greater impact. Distance vision remained stable, with only a minor myopic shift in the Vuity group. Intraocular pressure was unaffected, and no significant adverse effects were observed.
Reference
Mousavi SA, Rajavi Z, Sabbaghi H, et al. Pharmacological Treatment of Presbyopia Using Pilocarpine 1.25% Eye Drops. J Ophthalmic Vis Res. 2024;19(4):468-475. doi: 10.18502/jovr.v19i4.14578. PMID: 39917455; PMCID: PMC11795009.
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