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Glaucoma
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Novel real-time visualization OTC-based biometer yields positive results

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A new dynamic real-time visualization biometer exhibited intraobserver repeatability and interobserver reproducibility, according to a recent prospective observational study that compared 2 devices based on the swept-source optical coherence tomography (SS-OCT) principle. They had similar ocular parameters measurement values and can be interchanged in clinical practice, reported the researchers.

The dynamic real-time visualization 25 kHz SS-OCT-based biometer (ZW-30, TowardPi Medical Technology Ltd, China) and the SS-OCT-based biometer (IOLMaster 700, Carl Zeiss Meditec AG, Jena, Germany), were used in the study, which include 82 healthy right eyes. Measurements were repeated 3 times using both devices in a random order. Parameters included axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), lens thickness (LT), mean keratometry (Km), astigmatism magnitude (AST), vector J0, vector J45, and corneal diameter (CD). The within-subject standard deviation (Sw), test-retest (TRT) variability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were employed to assess the intraobserver repeatability and interobserver reproducibility. The double-angle plot was used to display the distribution of AST and Bland-Altman plots were used to estimate agreement.

For the intraobserver repeatability and interobserver reproducibility, the Sw, TRT and CoV for all parameters were low; while the ICC values were all close to 1.000, except for the J45. The double-angle plot showed that the distribution of AST measured by these 2 devices was similar. For agreement, the Bland-Altman plots showed narrow 95% limits of agreements of study parameters including AL, CCT, AQD, ACD, LT, Km AST, J0, J45, and CD.

Reference
Yu J, Lin X, Huang X, et al. Evaluation of a new dynamic real-time visualization 25 kHz swept-source optical coherence tomography based biometer. Eye Vis (Lond). 2024;11(1):9. doi:10.1186/s40662-024-00377-2