New spectacle lens design shows promising results in slowing myopia progression in children

Asymmetric Multi-point Defocus Technique (AMDT) spectacle lenses significantly slow myopia progression in children over 12 months compared to standard single vision lenses, with good safety and visual performance, according to a study.

In the double-masked randomized controlled trial, 140 participants aged 8 to 13 years with mild to moderate myopia were monitored over 12 months.

Children who wore AMDT lenses experienced an average myopia progression of -0.16 diopters (D) and an axial length increase of 0.17 mm over 12 months. In contrast, those wearing single vision lenses showed greater changes of -0.50 D and 0.32 mm, respectively. This represents a 74% reduction in refractive progression and a 51% reduction in axial elongation for the AMDT group.

Overall, 42.2% of those in the AMDT group showed no myopia progression at all over the study period.

The AMDT lenses were well tolerated, with no serious side effects or lasting visual discomfort. The age-related correlation with axial growth was less pronounced in the AMDT group.

Reference
Wang M, Ma R, Kuang L, et al. Myopia control efficacy of Asymmetric Multi-point Defocus Technique spectacle lenses: 1-year double-masked randomized controlled trial. Ophthalmology. 2025;S0161-6420(25)00272-6. doi: 10.1016/j.ophtha.2025.04.022. Epub ahead of print. PMID: 40306584.