Study finds both implantable collamer lens and small-incision lenticule extraction highly effective for low myopia

Both implantable collamer lens (ICL) surgery and small-incision lenticule extraction are highly effective, safe, and accurate for correcting low myopia, with small-incision lenticule extraction (SMILE) providing slightly better long-term predictability but a slower initial visual recovery compared to implantable collamer lens surgery, according to a presentation at AAO 2025.

Researchers analyzed 2,489 eyes receiving EVO+ ICL and 5,852 eyes treated with SMILE, ultimately matching 211 eyes per group for direct comparison.

Uncorrected distance visual acuity was similar between groups throughout the follow-up period. Patients with ICLs experienced rapid visual stabilization by 1 week, while SMILE patients showed slightly slower initial recovery but achieved comparable or slightly better long-term predictability. Spherical equivalent measurements at 6 weeks also showed no significant difference between the procedures.

The study concludes that both ICL and SMILE are safe, accurate, and effective options for correcting low myopia, with SMILE offering a modest edge in long-term predictability but a longer early recovery phase.

Reference
Redding CL, et al. Office-Based Cataract Surgery With Oral Sedation. Poster presented at: American Academy of Ophthalmology Annual Meeting; October 18–20, 2025; Orlando, FL.